ApoE ε4 Allele Related Alterations in Hippocampal Connectivity in Early Alzheimer’s Disease Support Memory Performance

Background: Whether the presence of the Apolipoprotein E ε4 allele modulates hippocampal connectivity networks in abnormal ageing has yet to be fully clarified. Keywords: Functional connectivity, disinhibition hypothesis, posterior cingulate, hippocampus; Alzheimer's disease, network disruption.