S1875 Epidemiologic Implications of Symptom Onset in Adults with Eosinophilic Esophagitis

in a scale from 0 (absence of the finding) to 5 (with a strong evidence of the finding): 1) Linear furrows along the organ (corrugated esophagus); 2) fragile mucosal appearance or “crepe paper” mucosa; 3) circular simultaneous contraction rings, and 4) irregular mucosa or “cobble stone-like pattern”. The data were analyzed using linear regression and were expressed as mean±SD, evaluating in parallel recordings obtained after and before indigocarmine staining. Results: 21 adult patients (20 males/1 female) aged between 16 and 56 year-old (mean 35.4) were studied. The marks were obtained from the questionnaire for each of these evaluated findings, before/after of the staining with indigo carmine (expressed as mean±SD): Linear longitudinal forrows: 2±1.4/4.2±1.12 (p<0.001); “crepe paper” mucosa: 1.4±1,4/2.3±1.6 (p<0.001); circular simultaneous contraction rings: 2±1.7/3±1.8 (p<0.001); and “cobble stone-like pattern”: 1.5±1.5/2.6±1.7 (p<0.001). Conclusion: Indigo carmine chromoendoscopy significantly highlights endoscopic mucosal findings in adult EE, by enhancing the mucosal irregularities, which results in an improvement in recognition of typical lesions. Systematic staining of mucosal surface in EE-suspected patients could improve the diagnostic guidance.