领域(数学分析)
免疫球蛋白轻链
化学
抗体
材料科学
数学
生物
遗传学
数学分析
作者
Lian Duan,Kowit Hengphasatporn,Takahiro Sakai,Ryo Fujiki,Norio Yoshida,Shun Hirota,Yasuteru Shigeta
标识
DOI:10.1021/acs.jpcb.4c03234
摘要
Misfolding of antibody light chains can lead to systemic light chain amyloidosis, which is associated with misfolding and aggregation. The antibody light chain may engage in 3D domain swapping within the variable region (#4V
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