医学
肌钙蛋白
无症状的
急性冠脉综合征
心脏外科
生物标志物
心脏毒性
内科学
重症监护医学
心脏病学
血管外科
临床意义
癌症
心肌梗塞
化疗
生物化学
化学
作者
Sebastian W. Romann,Evangelos Giannitsis,Norbert Frey,Lorenz Lehmann
标识
DOI:10.1007/s11897-024-00681-x
摘要
Abstract Purpose of the review Elevated troponin levels are well established e.g., for the diagnosis of suspected acute coronary syndrome in symptomatic patients. In contrast, troponin elevations in asymptomatic cancer patients emerge as a complex phenomenon, challenging traditional perceptions of its association solely with cardiac events. Recent findings Recent data support the predictive value of cardiac biomarker for all-cause mortality and cardiotoxicity in cancer patients. This review gives an overview about the current literature about cardiac troponins in prediction and identification of high-risk cancer patients. The overview is focusing on diagnostic challenges, biomarker significance, and gaps of knowledge. Summary Latest publications highlight the relevance of cardiac troponin in risk analysis before cancer treatment as well as a potential diagnostic gatekeeper for further cardiological diagnostics and therapy.
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