MEASUREMENT OF PARAMETERS CHARACTERIZING EARLY VASCULAR AGING WITH THE USE OF OSCILLOMETRIC METHOD DURING SPACE FLIGHT

The article covers the studies of the vascular wall functioning in cosmonauts using the data of pulse wave velocity as a biomarker of early vascular aging. The investigations were performed with the use of device Mobilograph twice before launch, every 30 days of 6-month ISS missions and on days 4 and 8 of recovery. Pulse wave velocity has never exceeded threshold values suggesting that participation in low-Earth orbital missions does not put at risk cardiac health threatening with vascular pathologies. Yet, the conclusion can be premature given the limited potentialities of the method and hardware used in the investigation.