[Analysis of reliability and validity of the Chinese version of reflux symptom score 12].

Objective: To standardize the 12-item reflux symptom scale in Chinese and evaluate its reliability, validity, and effect on diagnoses. Methods: A systematic translation version of the RSS-12 scale was performed using the Brislin model. The scale with 12 items included three dimensions of symptoms in ear, nose and throat, gastrointestinal tract and respiratory tract. The effect was assessed by three aspects containing symptom frequency, severity, and the quality of life. The Chinese version of RSS-12 was used to test 432 patients who attended the outpatient ENT department of Fujian Provincial Hospital between March 2021 and December 2021, and 413 patient questionnaires were classified as valid, aged 17-78(40.8±13.3) years, 203 were female and 210 were male. SPSS 26.0 and AMOS 24.0 statistical software were used to evaluate the performance of the scale. Results: The scale was highly discriminatory among items and correlated well among dimensions. The I-CVI ranged from 0.67 to 1.00, and the S-CVI was 0.81. The exploratory factor analysis showed that the cumulative variance contribution was 63.583%. The validation factor analysis showed that the model adaptation was good, and the correlation coefficient with the RSI was 0.796. Cronbach's α coefficient was 0.814, the retest reliability was 0.939, and the Spearman-Brown half reliability was 0.892, all of which showed a high level of reliability. Using 24h MII-pH as the diagnostic criterion for LPRD, the RSS-12 scale had a diagnostic compliance rate of 79.4%, with a sensitivity of 0.768 and specificity of 0.857. Conclusion: The Chinese version of the RSS-12 scale has good reliability, validity, and diagnostic ability, which can be used as a screening tool to diagnose pharyngeal reflux diseases.目的： 汉化反流症状评分-12（reflux symptom score 12，RSS-12）量表，并检验其信效度和诊断能力。 方法： 采用Brislin模式对RSS-12量表进行系统性翻译，量表包括耳鼻咽喉、消化道和呼吸道三个维度的症状，共12个条目，并从症状频率、严重程度及生活质量影响三个方面评估。用中文版RSS-12随机抽查2021年3月至12月间在福建省立医院门诊耳鼻咽喉头颈外科就诊的432例患者，其中413份为有效问卷，年龄17~78（40.8±13.3）岁，女性203例，男性210例。采用SPSS 26.0、AMOS 24.0统计学软件进行量表性能的分析。 结果： 量表各条目之间区分度高、与维度之间相关性较强。条目内容效度指数为0.67~1.00，总量表内容效度指数为0.81；经探索性因子分析的累计方差贡献率为63.583%，验证性因子分析结果显示模型适配度良好，与反流症状指数（RSI）量表效标相关系数为0.796；总量表Cronbach′s α系数为0.814，重测信度为0.939，Spearman-Brown折半信度为0.892，均表现出较高的信效度水平。以24 h多通道腔内阻抗pH（24 h MII-pH）为咽喉反流性疾病（LPRD）诊断标准，RSS-12量表诊断符合率79.4%，敏感性0.768、特异性0.857，总分大于20分判断为LPRD具有最高的诊断效能。 结论： 中文版RSS-12量表具有良好的信效度和诊断能力，可作为LPRD诊断的筛查工具。.