Family History of Colorectal Cancer and the Risk of Colorectal Neoplasia: A Systematic Review and Meta-analysis

Although there is enough pooled evidence supporting the positive association between family history of colorectal cancer (CRC) in first-degree relatives (FDRs) and the risk of CRC, synthesized data on its association with the risk of other colorectal neoplasia are lacking. Therefore, we aimed to systematically assess this issue.