磷光
荧光
材料科学
生物成像
生物相容性
纳米技术
吸收(声学)
纳米颗粒
持续发光
发光
分子
光化学
磷光有机发光二极管
化学
聚集诱导发射
激发态
光电子学
光学
有机化学
核物理学
冶金
复合材料
物理
热释光
作者
Jianhui Yang,Yahui Zhang,Xinghui Wu,Wenbo Dai,Dan Chen,Jianbing Shi,Bin Tong,Qian Peng,Hai‐Yan Xie,Zhengxu Cai,Yuping Dong,Xin Zhang
标识
DOI:10.1038/s41467-021-25174-6
摘要
Abstract Pure organic room-temperature phosphorescent (RTP) materials have been suggested to be promising bioimaging materials due to their good biocompatibility and long emission lifetime. Herein, we report a class of RTP materials. These materials are developed through the simple introduction of an aromatic carbonyl to a tetraphenylpyrrole molecule and also exhibit aggregation-induced emission (AIE) properties. These molecules show non-emission in solution and purely phosphorescent emission in the aggregated state, which are desirable properties for biological imaging. Highly crystalline nanoparticles can be easily fabricated with a long emission lifetime (20 μs), which eliminate background fluorescence interference from cells and tissues. The prepared nanoparticles demonstrate two-photon absorption characteristics and can be excited by near infrared (NIR) light, making them promising materials for deep-tissue optical imaging. This integrated aggregation-induced phosphorescence (AIP) strategy diversifies the existing pool of bioimaging agents to inspire the development of bioprobes in the future.
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