已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Efficacy and Safety of Intracavernosal Injection of Autologous Platelet Rich Plasma for Treatment of Erectile Dysfunction

医学 富血小板血浆 勃起功能障碍 血流动力学 他达拉非 舒张期 显著性差异 心脏病学 cGMP特异性磷酸二酯酶5型 动脉 内科学 泌尿科 勃起功能 血小板 血压
作者
Mohamed F. Raaia,Yasser Elkhiat,Ahmed Mohamed el Guindi,Mostafa A. El Gebaly,Ahmed M. Abdelhafez
出处
期刊:Indian Journal of Public Health Research and Development [Institute of Medico-legal Publications Private Limited]
卷期号:10 (12): 1460-1460 被引量:1
标识
DOI:10.37506/v10/i12/2019/ijphrd/192414
摘要

Purpose : This work aimed to evaluate the efficacy and safety of intracavernosal injection (ICI) of autologous platelet rich plasma (PRP) for the treatment of erectile dysfunction (ED). Method: This study included 30 patients (mean age 55.1) suffering from ED for more than 1 year. They were non-responders to oral phosphodiesterase type 5 (PDE5) inhibitors. Before initial therapy by PRP, all patients were subjected to history taking, examination and evaluation of erectile function (EF) using an abridged Arabic version of International Index of Erectile Function (IIEF-5). Additionally, patients were evaluated by Penile Color Doppler Ultrasonography (PCDUS). ICI of PRP was done once per week for 2 months.Follow up of EF and penile hemodynamics included evaluation of patients by IIEF-5 at 1, 2, 3 months and PCDUS at 3 months after initiation of therapy. Results: IIEF-5 score showed significant improvement at 1, 2 and 3 months after PRP injection. The injections improved the penile hemodynamics on both sides such that, the right peak systolic velocity (PSV), end diastolic velocity (EDV) and diameter of cavernosal artery differed after treatment compared to pre treatment levels (p value 0.012, 0.002 and 0.000) respectively. Also, PRP therapy improved the left side PSV, EDV and cavernosal artery diameter but the difference was statistically significant only in the left cavenosal EDV and cavernosal artery diameter (p value 0.002 and 0.000) respectively. Moreover, the results revealed a significant difference between response to ICI before and after treatment (p value 0.028) . Also, the treatment was well tolerated and no major side effects were reported. Conclusion: ICI of PRP could improve erectile function, penile hemodynamics, response to ICI, patient satisfaction and might be a salvage treatment for patients with severe erectile dysfunction who failed response to medical treatment.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
鲤鱼安青完成签到 ,获得积分10
2秒前
2秒前
2秒前
成就的笑南完成签到 ,获得积分10
6秒前
奕泽完成签到 ,获得积分10
6秒前
简单的红酒完成签到 ,获得积分10
7秒前
怡然乐巧发布了新的文献求助10
7秒前
虚幻沛菡完成签到 ,获得积分10
9秒前
王某人完成签到 ,获得积分10
10秒前
11秒前
16秒前
hhhhh完成签到 ,获得积分10
17秒前
小马甲应助洁净伟祺采纳,获得10
20秒前
科研搬运工完成签到,获得积分10
20秒前
23秒前
Billy应助科研通管家采纳,获得10
28秒前
坚强的广山应助科研通管家采纳,获得200
28秒前
顾矜应助科研通管家采纳,获得10
28秒前
31秒前
33秒前
范月月完成签到 ,获得积分10
35秒前
35秒前
梁33完成签到,获得积分10
35秒前
Jenny完成签到,获得积分10
36秒前
洁净伟祺发布了新的文献求助10
36秒前
37秒前
怡然乐巧发布了新的文献求助30
39秒前
40秒前
43秒前
Jae完成签到 ,获得积分10
45秒前
45秒前
寻道图强应助Billy采纳,获得30
46秒前
危机的幻柏完成签到,获得积分10
49秒前
52秒前
52秒前
qiqi1111发布了新的文献求助10
56秒前
温暖的弦完成签到,获得积分10
58秒前
啦啦啦完成签到 ,获得积分10
1分钟前
李健的小迷弟应助Ma采纳,获得10
1分钟前
寻道图强应助Billy采纳,获得30
1分钟前
高分求助中
Sustainability in ’Tides Chemistry 2000
Studien zur Ideengeschichte der Gesetzgebung 1000
The ACS Guide to Scholarly Communication 1000
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
Handbook of the Mammals of the World – Volume 3: Primates 805
Ethnicities: Media, Health, and Coping 800
Gerard de Lairesse : an artist between stage and studio 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3072510
求助须知:如何正确求助?哪些是违规求助? 2726292
关于积分的说明 7493477
捐赠科研通 2373949
什么是DOI,文献DOI怎么找? 1258829
科研通“疑难数据库(出版商)”最低求助积分说明 610392
版权声明 596983