认知
斯特罗普效应
随机对照试验
记忆广度
医学
认知训练
物理疗法
冲程(发动机)
物理医学与康复
康复
心理学
内科学
工作记忆
精神科
机械工程
工程类
作者
Wang Bo,Lei Mao,Tao Shen,Liu Tuan Jie,Qian Li,Fang Lin,Ping Wang
标识
DOI:10.1177/0269215518791007
摘要
Objective: This study evaluated the possible effect of the combined intervention of physical exercise and cognitive training on cognitive function in stroke survivals with vascular cognitive impairment. Design: A single-blind (investigator-blinded but not subject-blinded) randomized controlled trial. Setting: Medical Rehabilitation Center of Shanghai General Hospital, China. Subjects: A total of 225 patients (mean age 64.59 years, SD = 4.27) who exhibited vascular cognitive impairment were included in this study. Interventions: Patients were randomly allocated into one of the four groups: (1) physical exercise ( n = 56; 50-minute session), (2) cognitive training ( n = 57; 60-minute session), (3) combined intervention of physical exercise and cognitive training ( n = 55; 50-minute session + 60-minute session), or (4) control groups ( n = 57; 45-minute session). All participants received training for 36 sessions, three days per week, for 12 weeks. Primary measures: Measures were recorded at baseline, after the intervention and at a six-month follow-up. Primary measurements included the Trail Making Part B, Stroop, forward digit span, and mental rotation tests. Results: A total of 179 participants (79.56% response rate) completed the study. Cognitive performances on all four tasks in the combined training group improved significantly after the intervention ( P < 0.01). Changes in cognitive performance were greater in the combined intervention group than those in the physical exercise group (e.g. forward digit span, 13.61% vs. 2.18%, P = 0.003), the cognitive training group (e.g. mental rotation, 17.36% vs. 0.87%, P = 0.002), and the control group (e.g. Stroop, −4.11% vs. −0.72%, P = 0.026). Conclusion: The combined intervention produced greater benefits on cognitive function compared to either training alone in stroke survivors with vascular cognitive impairment.
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