Copper(I)-Catalyzed Enantioselective 1,4-Conjugate Hydrophos­phination of α,β-Unsaturated Esters

Abstract A copper-catalyzed enantioselective 1,4-conjugate hydrophosphination is achieved by employing α,β-unsaturated esters as electrophiles and diarylphosphines as pronucleophiles. An array of chiral phosphines was prepared in high to excellent enantioselectivity. Moreover, a triple catalytic symmetric conjugate hydrophosphination occurred smoothly to afford the product.