Efficacy of prognostic nutrition index in combination with D-dimer in predicting postoperative clinical adverse events after acute type A aortic dissection: a single center retrospective study

医学 不利影响 逻辑回归 接收机工作特性 单中心 回顾性队列研究 置信区间 内科学 外科 主动脉夹层 主动脉
作者
Linfeng Xie,Jian He,Xin‐fan Lin,Zhaofeng Zhang,Xinghui Zhuang,Debin Jiang
出处
期刊:Frontiers in Cardiovascular Medicine [Frontiers Media SA]
卷期号:10 被引量:2
标识
DOI:10.3389/fcvm.2023.1210725
摘要

The aim of this study was to identify the predictive factors for adverse clinical events after surgery in patients with acute type A aortic dissection (AAAD), and to explore the predictive value of preoperative prognostic nutritional index (PNI) combined with D-dimer for these events.This study was a retrospective analysis of clinical data of 153 patients with AAAD who underwent emergency surgery at our center from January 2019 to January 2022. Patients were divided into adverse event group and non-adverse event group based on whether they experienced adverse clinical events after surgery. Univariate and multivariable logistic regression analyses were performed to identify the risk factors for adverse events, and the predictive efficacy was evaluated by the area under the receiver operating characteristic curve (ROC-AUC).A total of 153 AAAD patients were included in the study, and were divided into the adverse event group (n = 46) and the non-adverse events group (n = 107) based on whether or not they experienced clinical adverse events after surgery. The optimal cutoff value was determined using ROC curves, and multivariate logistic regression analysis was performed. Ultimately, it was found that preoperative PNI < 42.45 and D-dimer > 15.05 were independent predictors of postoperative clinical adverse events in AAAD patients. The odd ratios (OR) value for preoperative PNI < 42.45 is 3.596 [95% Confidence Interval (CI): 1.508-8.923, p = 0.004], while the OR value for D-dimer > 15.05 is 7.572 [95% CI: 3.094-20.220, p < 0.001]. The combination of these two indicators has a high predictive value (AUC = 0.843, 95% CI: 0.774-0.912, p < 0.001) and is superior to using either variable alone.Preoperative PNI < 42.45 and D-dimer > 15.05 are independent predictive factors for postoperative adverse events during hospitalization in patients with AAAD. The combination of these two indicators can improve the predictive accuracy, which is superior to using either variable alone.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
1秒前
2秒前
炙热的羽毛完成签到,获得积分10
2秒前
baobeikk发布了新的文献求助10
2秒前
2秒前
guozizi完成签到,获得积分10
3秒前
卖火柴的小女孩完成签到,获得积分10
4秒前
4秒前
5秒前
一屿发布了新的文献求助10
5秒前
幽默从安发布了新的文献求助10
5秒前
guozizi发布了新的文献求助30
6秒前
11完成签到,获得积分10
7秒前
舒心夏山完成签到 ,获得积分10
7秒前
Wendy完成签到,获得积分10
7秒前
搜集达人应助高兴的忆曼采纳,获得10
8秒前
11发布了新的文献求助10
9秒前
CodeCraft应助dmyy313235采纳,获得30
9秒前
9秒前
聪明摩托完成签到,获得积分10
10秒前
迟大猫应助baobeikk采纳,获得10
10秒前
儒雅短靴发布了新的文献求助10
11秒前
Shelley发布了新的文献求助10
12秒前
不倦应助shiyi采纳,获得10
12秒前
崔佳鑫完成签到 ,获得积分10
12秒前
我不困完成签到,获得积分10
12秒前
啦啦累完成签到,获得积分0
12秒前
北地风情完成签到 ,获得积分10
13秒前
自由的寒香完成签到 ,获得积分10
13秒前
沙世平完成签到,获得积分10
13秒前
科研通AI2S应助Star1983采纳,获得10
13秒前
HEIKU举报WWWUBING求助涉嫌违规
14秒前
白安南发布了新的文献求助10
14秒前
LYC发布了新的文献求助10
15秒前
科研通AI2S应助宇宙的琴弦采纳,获得10
15秒前
北陌完成签到,获得积分10
17秒前
17秒前
曾泳钧完成签到,获得积分10
17秒前
微笑襄完成签到 ,获得积分10
18秒前
高分求助中
Continuum Thermodynamics and Material Modelling 3000
Production Logging: Theoretical and Interpretive Elements 2700
Les Mantodea de Guyane Insecta, Polyneoptera 1000
Structural Load Modelling and Combination for Performance and Safety Evaluation 1000
Conference Record, IAS Annual Meeting 1977 820
電気学会論文誌D(産業応用部門誌), 141 巻, 11 号 510
Typology of Conditional Constructions 500
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3571595
求助须知:如何正确求助?哪些是违规求助? 3142134
关于积分的说明 9445835
捐赠科研通 2843561
什么是DOI,文献DOI怎么找? 1562944
邀请新用户注册赠送积分活动 731458
科研通“疑难数据库(出版商)”最低求助积分说明 718551