Effects of Panax ginseng-containing herbal plasters on compressed intervertebral discs in an in vivo rat tail model

人参 体内 传统医学 针灸科 五加科 医学 生物 病理 替代医学 生物技术
作者
Dhk Chow,Alon Lai,Fuk Tang,Mason C P Leung
出处
期刊:Chinese Medicine [BioMed Central]
卷期号:8 (1) 被引量:4
标识
DOI:10.1186/1749-8546-8-4
摘要

Tienchi (Panax notoginseng) has been used in conservative treatments for back pain as a major ingredient of many herbal medicines. This study aims to investigate the effects of a herbal medicine containing tienchi on compressed intervertebral discs in rats.Using an in vivo rat tail model, intervertebral disc compression was simulated in the caudal 8-9 discs of 25 rats by continuous static compression (11 N) for 2 weeks. An herbal medicine plaster (in which the major ingredient was tienchi) was externally applied to the compressed disc (n=9) for three weeks, and held in place by an adhesive bandage, in animals in the Chinese Medicine (CM) group. The effect of the bandage was evaluated in a separate placebo group (n=9), while no intervention with unrestricted motion was provided to rats in an additional control group (n=7). Disc structural properties were quantified by in vivo disc height measurement and in vitro morphological analysis.Disc height decreased after the application of compression (P < 0.001). The disc height decreased continuously in the control (P = 0.006) and placebo (P = 0.003) groups, but was maintained in the CM group (P = 0.494). No obvious differences in disc morphology were observed among the three groups (P = 0.896).The tienchi-containing herbal plaster had no significant effect on the morphology of compressed discs, but maintained disc height in rats.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
彭栋发布了新的文献求助10
1秒前
所所应助萨日呼采纳,获得10
2秒前
4秒前
隐形曼青应助hh采纳,获得50
6秒前
义气如萱发布了新的文献求助10
7秒前
小俊完成签到,获得积分10
9秒前
Nana发布了新的文献求助20
10秒前
小二郎应助修管子采纳,获得10
11秒前
mie完成签到,获得积分10
14秒前
14秒前
15秒前
寄语明月发布了新的文献求助10
17秒前
hh发布了新的文献求助50
19秒前
mie发布了新的文献求助10
19秒前
CipherSage应助wu基督教采纳,获得10
20秒前
lalala完成签到,获得积分10
21秒前
科研通AI5应助Bressanone采纳,获得10
22秒前
22秒前
24秒前
FashionBoy应助anna采纳,获得10
29秒前
29秒前
31秒前
大智若愚骨头完成签到,获得积分10
32秒前
32秒前
35秒前
量子星尘发布了新的文献求助10
35秒前
9℃发布了新的文献求助10
35秒前
科研通AI2S应助lm采纳,获得10
36秒前
山谷发布了新的文献求助10
37秒前
感动黄豆发布了新的文献求助10
39秒前
41秒前
42秒前
42秒前
42秒前
44秒前
Owen应助晒太阳的加菲猫采纳,获得10
45秒前
anna发布了新的文献求助10
47秒前
47秒前
wu基督教发布了新的文献求助10
48秒前
49秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989115
求助须知:如何正确求助?哪些是违规求助? 3531367
关于积分的说明 11253688
捐赠科研通 3269986
什么是DOI,文献DOI怎么找? 1804868
邀请新用户注册赠送积分活动 882078
科研通“疑难数据库(出版商)”最低求助积分说明 809105