医学
针灸科
纳入和排除标准
随机对照试验
多囊卵巢
观察研究
内科学
不利影响
科克伦图书馆
梅德林
心理干预
胰岛素
妇科
胰岛素抵抗
替代医学
病理
精神科
法学
政治学
作者
Chi Eung Danforn Lim,Wu Shun Felix Wong
标识
DOI:10.3109/09513591003686304
摘要
Objective. This paper aims to provide a literature review on evaluating the efficacy of acupuncture therapy in the treatment of polycystic ovarian syndrome (PCOS) by reviewing clinical trials; randomised and non-randomised and observational studies on PCOS. The paper will also determine the possible mechanism of acupuncture treatment in PCOS, limitations of recruited studies and suggest further improvements in future studies.Design. A comprehensive literature search was conducted through the databases Medline, PubMed, EMBASE, Cochrane, AMED (Allied and Complementary Medicine), NCCAM (The National Centre for Complementary and Alternative Medicine) to identify relevant monographs.Results. Four studies were recruited. Several studies showed that acupuncture significantly increases β-endorphin levels for periods up to 24 h and may have regulatory effect on FSH, LH and androgen. β-endorphin increased levels secondary to acupuncture affects the hyperthalamic–pituitary–adrenal (HPA) axis through promoting the release of ACTH through stimulation of its precursor pro-opiomelanocortin synthesis.Inclusion criteria. All available acupuncture studies on human subjects with PCOS from June 1970 to June 2009.Exclusion criteria. Studies not meeting the inclusion criteria, published in languages other than English or animal studies.Conclusion. Acupuncture is a safe and effective treatment to PCOS as the adverse effects of pharmacologic interventions are not expected by women with PCOS. Acupuncture therapy may have a role in PCOS by: increasing of blood flow to the ovaries, reducing of ovarian volume and the number of ovarian cysts, controlling hyperglycaemia through increasing insulin sensitivity and decreasing blood glucose and insulin levels, reducing cortisol levels and assisting in weight loss and anorexia. However, well-designed, randomised controlled trials are needed to elucidate the true effect of acupuncture on PCOS.
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