作者
Hang Zhao,Weicen Chen,Yongxiang Li,Hailiang Wang,Hanfei Li,T. Li,Fei Han,Jing Sun,Laixin Huang,Xinhao Peng,Jianzhong Chen,Yihang Yang,Xin Qiu,Yan Liu,Huan Yu,Wen‐Hsien Hou,Qingsong Li,Guibing Fu,Chao You,Xijian Liu,Fei Li,Xiangxin Li,Guoru Zhao,Lin Wang,Peng Fang,Guanglin Li,Hairong Zheng,Meifang Zhu,Wei Yan,Qiong Tian,Teng Ma,Zhiyuan Liu
摘要
Neuromuscular abnormality is the leading cause of disability in adults. Understanding the complex interplay between muscle structure and function is crucial for effective treatment and rehabilitation. However, the substantial deformation of muscles during movement (up to 40%) poses challenges for accurate assessment. To address this, we developed a wearable structural-functional sensing patch (WSFP) that enables synchronous analysis of muscle structure and function. The WSFP incorporates a soft, stretchable electrode array for high-performance electrophysiological monitoring with low contact impedance and high stability. Its innovative design absorbs skin deformation stress, ensuring stable adhesion of a flexible ultrasound transducer array, offering higher-fidelity imaging. With dynamic tissue imaging, it allows real-time visualization of muscle structure. The WSFP achieves superior accuracy in dynamic action recognition and disease assessment compared to single-modal methods, maintaining stable operation during motion for up to 72 hours. This study advances neuromuscular system analysis and improves diagnostic precision.