Arene ruthenium(ii) complexes with chalcone, aminoantipyrine and aminopyrimidine based ligands: synthesis, structure and preliminary evaluation of anti-leukemia activity

A series of arene ruthenium(ii) complexes withN-monodentate (AAP) andN,O- andN,N-bidentate chelating ligands (AAPS, ADABS, AAPPA and P2P) have been synthesized and evaluated for preliminary antileukemia activity against K562 (Human chronic myeloid leukemia cell line).