A new secoiridoid glycoside from Picrorhiza scrophulariiflora

Objective To study the constituents in the roots of Picrorhiza scrophulariiflora.Methods The constituents of P.scrophulariiflora were separated and purified with chromatographic methods.The structures were elucidated by spectroscopic methods and chemical analyses.Results Four compounds isolated from the 90% ethanol extract in the roots of P.scrophulariiflora were identified as picrogentioside D(1),sweroside(2),gentiopicroside(3),and mannitol(4).Conclusion Compounds 1—4 are obtained from the roots of P.scrophulariiflora for the first time and compound 1 is a new secoiridoid glycoside,named picrogentioside D.