氯诺昔康
化学
色谱法
质谱法
元素分析
高效液相色谱法
溶解度
分析化学(期刊)
物理化学
有机化学
药理学
医学
止痛药
作者
Mahrous O. Ahmed,Abdullah A. Al‐Badr
出处
期刊:Profiles of Drug Substances, Excipients and Related Methodology
日期:2011-01-01
卷期号:: 205-239
被引量:19
标识
DOI:10.1016/b978-0-12-387667-6.00006-3
摘要
A comprehensive profile on lornoxicam, the oxicam nonsteroidal anti-inflammatory agent which is used in the muscular skeletal and joint disorders such as osteoarthritis and rheumatoid arthritis, is prepared. This profile contains the following sections: description, uses and applications, methods of preparation, physical characteristics, methods of analysis, mechanism of action, pharmacokinetics, reviews, and stability. The physical characteristics section includes ionization constant, solubility, partition coefficient, thermal methods of analysis. X-ray powder diffraction pattern, crystal structure, ultraviolet spectroscopy, vibrational spectroscopy, proton and carbon-13 nuclear magnetic resonance spectrometry, and mass spectrometry. Methods of analysis section includes spectrophotometry, polarography, and chromatography (TLC, HPLC, HPLC-MS).
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