医学
心肺适能
中性粒细胞与淋巴细胞比率
内科学
发病机制
痹症科
疾病
败血症
淋巴细胞
萎缩
纤维化
胃肠病学
免疫学
作者
Noha Esheba,Abeer Shahba
出处
期刊:Egyptian Journal of Rheumatology & Clinical Immunology
日期:2015-12-01
卷期号:3 (1): 33-41
被引量:3
标识
DOI:10.21608/ejrci.2015.4475
摘要
Introduction: Systemic sclerosis (SSc) is a multisystem autoimmune disease, with complex pathogenesis resulting inobliterative vasculopathy, tissue injury, fibrosis, remodeling and atrophy. The neutrophil lymphocyte ratio (NLR) wasdeveloped to provide easily measurable and readily available parameter reflecting the intensity of stress and systemicinflammation in critically ill patients following shock, multiple traumas, major surgery, or sepsis. Aim of the work: toevaluate NLR levels in patients with SSc and explore their clinical significance and their association with different organmanifestations. Results: There was a significant increase in NLR in SSc patients who had cardiovascular or cardiorespiratory affection. Also NLR showed a significant positive correlation with both CRP and ESR, while it showed a significant negative correlation with serum albumin. Conclusion: NLR may serve as a promising marker for cardiorespiratory involvement in SSc patients. [Egypt J Rheumatology & Clinical Immunology, 2016; 4(1): 43-47]
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