Preliminary study of spectral CT in benign and malignant lung lesions

Objective To investigate the value of spectral CT for the discrimination of benign and malignant lung lesions through multi-parameter quantitative measurement. Methods Eighty-one patients who had lung nodule or mass on X-ray or plain CT were scanned using spectral CT,generating iodine concentration,water concentration and 101 sets of monochromatic images.Iodine concentration,water concentration,spectrum energy curve and CT value at 40 keV were measured with spectral postprocessing software.70 eligible patients were divided into pneumonia group and tumor group.ANOVA analysis was used for the statistic analysis in two groups. Results The iodine concentration in pneumonia group and tumor group were (1.47±0.17) and (0.77±0.19) g/L (F=203.97,P 0.05),there was no significant difference. Conclusion Spectral CT technique has very important value for the discrimination of benign and malignant lung lesions. Key words: Lung neoplasms; Pneumonia; Tomography,X-ray computed