Aromatic C–H Amination Using Alkyl Amines

Reactions assembling C–N bonds on aromatic rings are routinely used to construct anilines, but they usually require the prefunctionalization of the arene to enable cross-couplings like Buchwald–Hartwig or Chan–Lam. Direct aromatic C–H amination protocols are highly sought after but still elusive. Our group has developed a photoredox strategy that enables direct and selective aromatic amination using unfunctionalized arenes and alkyl amines.