A new prenylcoumarin was isolated from the leaves of Murraya paniculata (Rutaceae), and its structure was elucidated as 5, 7-dimethoxy-8-[(Z)-3'-methylbutan-1', 3'-dienyl]coumarin on the basis of spectroscopic evidence.Five other coumarins were also obtained and identified with the known compounds coumurrayin, 5, 7-dimethoxy-8-(3'-methyl-2'-oxobutyl)coumarin, toddalenone, toddasin and aurapten.