胚状体
生物
胚胎干细胞
血管母细胞
细胞生物学
干细胞
细胞分化
造血
成体干细胞
内皮干细胞
谱系(遗传)
体外
遗传学
基因
标识
DOI:10.1016/0955-0674(95)80071-9
摘要
Under appropriate conditions in culture, embryonic stem cells will differentiate and form embryoid bodies that have been shown to contain cells of the hematopoietic, endothelial, muscle and neuronal lineages. Many aspects of the lineage-specific differentiation programs observed within the embryoid bodies reflect those found in the embryo, indicating that this model system provides access to early cell populations that develop in a normal fashion. Recent studies involving the differentiation of genetically altered embryonic stem cells highlight the potential of this in vitro differentiation system for defining the function of genes in early development.
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