Enzyme confined in silica-based nanocages for biocatalysis in a Pickering emulsion

The encapsulation of lipase into the nanocages of FDU-12 and the amphiphilic modification of the surfaces of FDU-12 can concurrently be accomplished via a facile silylation method. The obtained lipase-loaded FDU-12 particles featuring superior biocatalytic activity and negligible enzyme leaching can serve as efficient stabilizers for a Pickering emulsion to enhance the performance of biphasic enzymatic reactions.