同种异体移植
CD8型
背景(考古学)
移植
细胞毒性T细胞
免疫学
T细胞
生物
医学
免疫系统
内科学
遗传学
体外
古生物学
作者
Michael Nicosia,Anna Valujskikh
出处
期刊:Transplantation
[Ovid Technologies (Wolters Kluwer)]
日期:2024-04-19
卷期号:108 (11): 2186-2196
被引量:1
标识
DOI:10.1097/tp.0000000000005001
摘要
The major role of CD8 + T cells in clinical and experimental transplantation is well documented and acknowledged. Nevertheless, the precise impact of CD8 + T cells on graft tissue injury is not completely understood, thus impeding the development of specific treatment strategies. The goal of this overview is to consider the biology and functions of CD8 + T cells in the context of experimental and clinical allotransplantation, with special emphasis on how this cell subset is affected by currently available and emerging therapies.
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