医学
核医学
前瞻性队列研究
胃肠病学
腺癌
显著性差异
窄带成像
癌症
内科学
内窥镜检查
作者
Osamu Dohi,Nobuaki Yagi,Shigeto Yoshida,Shoko Ono,Yoji Sanomura,Shinji Tanaka,Yuji Naito,Mototsugu Kato
出处
期刊:Digestion
[S. Karger AG]
日期:2017-01-01
卷期号:96 (3): 127-134
被引量:35
摘要
<b><i>Background/Aims:</i></b> The diagnostic efficacy of magnifying blue laser imaging (M-BLI) and M-BLI in bright mode (M-BLI-bright) in the identification of early gastric cancer (EGC) was evaluated for comparison to that of magnifying narrow-band imaging (M-NBI). <b><i>Methods:</i></b> This prospective, multicenter study evaluated 114 gastric lesions examined using M-BLI, M-BLI-bright, and M-NBI between May 2012 and November 2012; 104 EGCs were evaluated by each modality. The vessel plus surface classification system was used to evaluate the demarcation line (DL), microvascular pattern (MVP), and microsurface pattern (MSP). <b><i>Results:</i></b> M-BLI, M-BLI-bright, and M-NBI revealed a DL for 96.1, 98.1, and 98.1% and irregular MVP for 95.1, 95.1, and 96.2% of lesions, respectively, with no significant difference. Irregular MSP was observed by M-BLI, M-BLI-bright, and M-NBI in 97.1, 90.4, and 78.8% of lesions, respectively, with significant differences (<i>p</i> < 0.001). The proportion of moderately differentiated adenocarcinoma with irregular MSP on M-BLI and absent MSP on M-NBI was significantly higher than that with irregular MSP on M-BLI and M-NBI (35.0 and 9.9%, respectively; <i>p</i> = 0.002). <b><i>Conclusion:</i></b> M-BLI and M-BLI-bright provided excellent visualization of microstructures and microvessels similar to M-NBI. Irregular MSP in a moderately differentiated adenocarcinoma might be frequently visualized using M-BLI and M-BLI-bright compared with using M-NBI.
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