Air Quality Index and Emergency Department Visits and Hospitalizations in Children with Asthma: A Time-Stratified Case-Crossover Study in Pittsburgh

急诊科 哮喘 医学 索引(排版) 渡线 交叉研究 急诊医学 医疗急救 计算机科学 内科学 人工智能 护理部 替代医学 病理 万维网 安慰剂
作者
Franziska Rosser,Yueh‐Ying Han,Scott D. Rothenberger,Erick Forno,Christina Mair,Juan C. Celedón
标识
DOI:10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3169
摘要

Introduction: Outdoor air pollution is a known cause of childhood asthma exacerbations.In the United States, the Air Quality Index (AQI) is meant to alert the public to air quality and provide behavioral recommendations to reduce risk of harm.The association between the AQI and severe asthma exacerbations in US children is unknown.Methods: Using medical record data from UPMC Children's Hospital of Pittsburgh for 2010-2018, we conducted a time-stratified case-crossover study of emergency department (ED) visits and hospitalizations with a primary diagnosis code of asthma exacerbation for children aged 6 to 17 years.Environmental Protection Agency air quality data was obtained as daily overall AQI and for each of 5 criteria pollutants.AQI values on the day of event and the preceding 5 days (lag days) were evaluated.Conditional logistic regression was used for analyses, adjusting for meteorological variables.Effect modification was evaluated by stratification.Results: There were 6,573 events from 3,344 unique persons.The average age at time of event was 10 years; 57.2% were Black and 58.7% were male.Most events (n=4,431 (67.4% of total) occurred in 35.9% of persons.Particulate matter <2.5m (PM 2.5 ) was primarily responsible for the overall AQI, followed by ozone, and sulfur dioxide (61%, 29%, and 8% of days with events respectively).Half of all days were in the 'Moderate' category, (49%) followed by 'Good' (41.5%); fewer were in 'Unhealthy for Sensitive Groups' (8.5%) or 'Unhealthy' (1.1%).Overall AQI category in the prior 2 days was associated with increased odds of ED visits/hospitalizations (lag day 2: OR 1.05 95% CI 1.00-1.09p= 0.04) for which PM 2.5 was primarily responsible (OR 1.06 95% CI 1.01-1.11p=0.03).The overall AQI, per 10 unit increase, was associated with increased events on lag days 2 and 3; these were significant for PM 2.5 , PM 10 , and sulfur dioxide.Effect modification was seen for AQI (continuous) for those with >1 event (Lag 2 OR 1.01, 95% CI 1.00-1.03P=0.05), aged 12-17 years (Lag 2: OR 1.02, 95%CI 1.00-1.03p=0.04), and Black children (Lag 2: OR 1.02, 95%CI 1.00-1.03p= 0.009, Lag 3: OR 1.01, 95%CI 1.00-1.03p=0.04,Lag 4: OR 1.02, 95%CI 1.00-1.03p=0.02).Conclusions: The overall air quality index is associated with ED visits and hospitalizations for asthma exacerbations in children in Allegheny County, PA, even for levels in the Good and Moderate ranges.Prospective studies evaluating the efficacy of AQI in preventing severe childhood asthma exacerbations are needed

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
酷酷李可爱婕完成签到 ,获得积分10
刚刚
英姑应助白白采纳,获得10
1秒前
满座完成签到,获得积分10
2秒前
杨羕完成签到,获得积分10
3秒前
五六七完成签到,获得积分10
3秒前
周少完成签到,获得积分10
3秒前
兴奋的若菱完成签到 ,获得积分10
3秒前
幸福广山完成签到,获得积分10
5秒前
HMethod完成签到 ,获得积分10
7秒前
Y123完成签到,获得积分10
7秒前
8秒前
ersan完成签到,获得积分10
9秒前
Hello应助nkmenghan采纳,获得30
10秒前
10秒前
10秒前
粗心的听安完成签到,获得积分10
10秒前
念姬完成签到 ,获得积分10
11秒前
量子星尘发布了新的文献求助10
11秒前
12秒前
13秒前
指哪打哪完成签到,获得积分10
13秒前
13秒前
静静子发布了新的文献求助100
14秒前
Ray完成签到 ,获得积分10
15秒前
文静的天蓝完成签到,获得积分10
15秒前
tszjw168完成签到 ,获得积分10
16秒前
手打鱼丸完成签到 ,获得积分10
17秒前
体贴凌柏发布了新的文献求助10
17秒前
开心快乐发大财完成签到,获得积分10
19秒前
萌萌哒完成签到,获得积分10
19秒前
小龅牙吖完成签到,获得积分10
19秒前
Propitious完成签到,获得积分10
20秒前
徐先生1106完成签到,获得积分10
20秒前
Epiphany完成签到,获得积分10
21秒前
舒心的久完成签到 ,获得积分10
21秒前
闻巷雨完成签到 ,获得积分10
23秒前
北风完成签到,获得积分10
24秒前
xliiii完成签到,获得积分10
24秒前
时光倒流的鱼完成签到,获得积分10
25秒前
LL完成签到,获得积分10
25秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038303
求助须知:如何正确求助?哪些是违规求助? 3576013
关于积分的说明 11374210
捐赠科研通 3305780
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029