Effect of Different Treatments for Intracranial Solitary Fibrous Tumors: Retrospective Analysis of 31 Patients

医学 孤立性纤维性肿瘤 危险系数 回顾性队列研究 天幕 单变量分析 比例危险模型 放射外科 多元分析 脑转移 放射治疗 病历 转移 外科 内科学 置信区间 癌症 川地34 生物 遗传学 干细胞
作者
Qinghua Li,Wenshui Deng,Peng Sun
出处
期刊:World Neurosurgery [Elsevier BV]
卷期号:166: e60-e69 被引量:4
标识
DOI:10.1016/j.wneu.2022.06.089
摘要

An intracranial solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm with a high predisposition toward recurrence and metastasis. The definition of SFT was updated according to the 2021 World Health Organization (WHO) classification. Given its rarity and resemblance to meningiomas, SFT is often misdiagnosed and there remains a debate on the treatment for it. We provide a retrospective analysis of SFTs and conclude the outcomes of different treatments.Patients who accepted operation and were diagnosed with intracranial SFTs in our hospital were included between 2008 and 2021. The medical records on clinical characteristics and outcomes were summarized for analysis. Cox regressions were used to determine the hazard ratio (HR).Thirty-one SFT patients were included with a median follow-up time of 67 months. Tumor recurrence was observed in 12 (38.7%) patients, with 1 and 5-year recurrence rates of 6.5% and 22.6%, respectively. In univariate analysis, gross total resection (GTR) was significantly associated with decreased recurrence (P = 0.022), while subtotal resection (STR) (HR = 9.237; P = 0.020) and tumor location of tentorium (HR = 4.692; P = 0.022) were correlated with increased recurrence. In multivariate analysis, GTR (P = 0.040) and GTR plus radiotherapy (GTR + RT) (HR = 0.002; P = 0.020) were associated with reduced recurrence, while STR (HR = 40.835; P = 0.012) was a risk factor for recurrence.GTR and postoperative RT are beneficial for preventing tumor recurrence. Larger studies and long-term follow-up are warranted to further identify the effect of postoperative RT.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
111发布了新的文献求助10
刚刚
zgnh完成签到,获得积分10
刚刚
希望天下0贩的0应助Younglee采纳,获得10
刚刚
温婉的钢铁侠完成签到 ,获得积分10
刚刚
黑森林发布了新的文献求助20
刚刚
赫连紫完成签到,获得积分10
1秒前
发飙的牛发布了新的文献求助10
1秒前
英俊的铭应助小西米采纳,获得10
1秒前
2秒前
2秒前
可积发布了新的文献求助10
3秒前
3秒前
hanzhangjian完成签到,获得积分10
4秒前
含蓄丸子发布了新的文献求助10
5秒前
6秒前
志明完成签到,获得积分10
6秒前
QQ完成签到,获得积分10
7秒前
heheha完成签到,获得积分10
7秒前
7秒前
简单的平松完成签到,获得积分10
7秒前
biozy发布了新的文献求助10
8秒前
wang完成签到,获得积分10
8秒前
小嘎完成签到 ,获得积分10
8秒前
执着怜珊完成签到 ,获得积分10
9秒前
tywznba发布了新的文献求助10
9秒前
orixero应助勤劳的斑马采纳,获得10
10秒前
10秒前
Fang Xianxin完成签到,获得积分10
10秒前
10秒前
10秒前
谦让的焱发布了新的文献求助100
10秒前
wxy完成签到 ,获得积分10
11秒前
土豆丝发布了新的文献求助10
11秒前
11秒前
优雅烨伟发布了新的文献求助10
11秒前
12秒前
epoch完成签到,获得积分10
12秒前
guoke发布了新的文献求助20
13秒前
13秒前
djbj2022发布了新的文献求助30
14秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3969322
求助须知:如何正确求助?哪些是违规求助? 3514152
关于积分的说明 11172188
捐赠科研通 3249407
什么是DOI,文献DOI怎么找? 1794832
邀请新用户注册赠送积分活动 875437
科研通“疑难数据库(出版商)”最低求助积分说明 804781