重症监护医学
医学
曲菌病
背景(考古学)
重症监护室
流行病学
病危
疾病
免疫学
病理
生物
古生物学
作者
Sarah Gaffney,Dearbhla Kelly,Puteri Maisarah Rameli,Eoin Kelleher,Ignacio Martín‐Loeches
出处
期刊:Apmis
[Wiley]
日期:2023-04-06
卷期号:131 (11): 654-667
被引量:2
摘要
The prevalence of invasive pulmonary aspergillosis (IPA) is growing in critically ill patients in the intensive care unit (ICU). It is increasingly recognized in immunocompetent hosts and immunocompromised ones. IPA frequently complicates both severe influenza and severe coronavirus disease 2019 (COVID-19) infection. It continues to represent both a diagnostic and therapeutic challenge and can be associated with significant morbidity and mortality. In this narrative review, we describe the epidemiology, risk factors and disease manifestations of IPA. We discuss the latest evidence and current published guidelines for the diagnosis and management of IPA in the context of the critically ill within the ICU. Finally, we review influenza-associated pulmonary aspergillosis (IAPA), COVID-19-associated pulmonary aspergillosis (CAPA) as well as ongoing and future areas of research.
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