生物
群体感应
次生代谢
适应(眼睛)
内生菌
寄主(生物学)
代谢途径
基因
计算生物学
生物合成
生态学
生物化学
植物
毒力
神经科学
作者
Garima Sharma,Surbhi Agarwal,K. S. Verma,Rashmi Bhardwaj,V. K. Mathur
标识
DOI:10.1093/jambio/lxad074
摘要
Abstract During the last few decades, endophytes have attracted increased attention due to their ability to produce a plethora of bioactive secondary metabolites. These compounds not only help the endophytes to outcompete other plant-associated microbes or pathogens through quorum sensing, but also enable them to surmount the plant immune system. However, only a very few studies have described the interlink between various biochemical and molecular factors of host-microbe interactions involved in the production of these pharmacological metabolites. The peculiar mechanisms by which endophytes modulate plant physiology and metabolism through elicitors, as well as how they use transitional compounds of primary and secondary metabolism as nutrients and precursors for the synthesis of new compounds or enhancing existing metabolites, are still less understood. This study thus attempts to address the aspects of synthesis of such metabolites used in therapeutics by the endophytes in the light of their ecological significance, adaptation, and intercommunity interactions. Our study explores how endophytes adapt to the specific host environment, especially in medicinal plants that produce metabolites with pharmacological potential and simultaneously modulate host gene expression for the biosynthesis of these metabolites. We also discuss the differential interactions of fungal and bacterial endophytes with their hosts.
科研通智能强力驱动
Strongly Powered by AbleSci AI