化学
溶解度
共晶体系
药剂学
活性成分
药品
药物输送
生化工程
环境友好型
药理学
纳米技术
工艺工程
组合化学
有机化学
工程类
材料科学
医学
合金
生态学
生物
作者
Anshu Sharma,Yea Rock Park,Aman Garg,Bong‐Seop Lee
标识
DOI:10.1021/acs.jmedchem.4c01550
摘要
Deep eutectic solvents (DES) are environmentally friendly solvents with the potential to dissolve bioactive compounds without affecting their characteristics. DES has special qualities that can be customized to meet the unique characteristics of a biomolecule/active pharmaceutical ingredient (API) in accordance with various therapeutic needs, providing a reliable approach in opening the door for the creation of cutting-edge drug formulations by resolving solubility issues in pharmaceutics. This study outlines newly developing approaches to solve the problem of inefficient API extraction due to poor solubility. These emerging strategies also have the capacity to alter the chemical and physical stability of API, which triggers drug's shelf life and their possible health benefits. It is anticipated that the highlighted methods and processes will be developed to capitalize on the DES potential to improve drug solubility and delivery in the pharmaceutical sector.
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