化疗
免疫系统
胃
内科学
医学
胃癌
白细胞介素2
胃肠病学
癌症
淋巴因子激活杀伤细胞
淋巴因子
自然杀伤细胞
受体
免疫学
肿瘤科
T细胞
生物
细胞毒性T细胞
白细胞介素21
体外
生物化学
作者
Shen Lin,L. M. Liu,Lixia Wu
出处
期刊:PubMed
日期:1995-08-01
卷期号:15 (8): 451-3
被引量:18
摘要
Sixty-three cases with stomach cancer were randomized and observed, the results showed that the count of T lymphocytes in chemotherapy combined with Shenmai injection (SMI) group increased, while in control group it decreased, the difference was significant (P < 0.05). The results also indicated that the count of OKT4 cells and the ratio of OKT4/OKT8 decreased after chemotherapy, but in SMI group both parameters increased in advence which were higher in the 4th week after chemotherapy than that before chemotherapy. However, the count of OKT1 cells and the ratio of OKT4/OKT8 were still in low level. Serum interleukin-2 receptor (sIL-2R) level also decreased (P < 0.05), while activities of natural killer cell (NK) and lymphokine activated killer cell (LAK) level increased (P < 0.05) in SMI group. Although the sIL-2R level had no change, both NK and LAK level decreased in control group. In addition, the difference of IgA, IgM, IgG level were not significant between these two groups. This suggested that SMI might improve human immune function to facilitate the chemotherapy of patients with stomach cancer.
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