红曲饭
洛伐他汀
医学
肝损伤
酵母
甲基强的松龙
肝活检
肝炎
内科学
药品
胃肠病学
药理学
胆固醇
活检
生物化学
生物
病理
替代医学
作者
Lize Loubser,Kirstin I Weider,Sean Drake
出处
期刊:Case Reports
[BMJ]
日期:2019-03-01
卷期号:12 (3): e227961-e227961
被引量:17
标识
DOI:10.1136/bcr-2018-227961
摘要
A 64-year-old woman previously taking no medications presented with acute hepatitis 6 weeks after starting a red yeast rice supplement to decrease her cholesterol. Red yeast rice is commonly used for hyperlipidaemia as an alternative to statins as it contains monacolin K, the same active chemical in lovastatin. Infectious, toxic and autoimmune causes for injury were ruled out, and liver biopsy was consistent with drug induced liver injury. Red yeast rice appeared to be the cause of her hepatotoxicity. After stopping the supplement and initiating treatment with intravenous methylprednisolone, liver enzymes decreased towards baseline.
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