细胞
干细胞
生化工程
生物技术
计算机科学
生物
细胞生物学
工程类
生物化学
作者
Nathalie J. Robinson,Andrew Picken,Karen Coopman
标识
DOI:10.1007/s10529-013-1349-5
摘要
Encouraging advances in cell therapies have produced a requirement for an effective short-term cell preservation method, enabling time for quality assurance testing and transport to their clinical destination. Low temperature pausing of cells offers many advantages over cryopreservation, including the ability to store cells at scale, reduced cost and a simplified procedure with increased reliability. This review will focus on the importance of developing a short-term cell preservation platform as well highlighting the major successes of cell pausing and the key challenges which need addressing, to enable application of the process to therapeutically relevant cells.
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