Zinc (Ⅱ) functionalized magnetic geopolymer as sorbents for rapid extraction of Fluoroquinolones in food prior to quantification by UHPLC-MS/MS

A novel Zn@MGeo sorbent was easily constructed and can bind with FQs through the synergistic effect of electrostatic interaction and coordination. With the Zn@MGeo as sorbent, a MSPE-UHPLC-MS/MS method was established for simultaneous detection of FQs in complex matrices. The whole extraction process could be completed using 6.0 mg sorbent within 10 min under the optimal conditions. The established quantitative method obtained a wide linear range (0.01-200 μg/kg, R2 > 0.9987), high sensitivity (LODs: 0.005-0.05 μg/kg) and negligible matrix effect. The method was applied for analysis of real samples, with recoveries between 75.6% and 103.7%. In addition, the sorbent could be reused at least 9 times without reducing the adsorption performance. In general, the established method not only proposes a novel sorbent for FQs extraction, but also provides a powerful tool for rapid and sensitive detection of FQs in food matrices with practical application value.