P1.15-01 Differential Diagnosis of Pneumonitis in Metastatic NSCLC (Non-Small Cell Lung Cancer) Patients Receiving Immunotherapy With Radiomics

Immunotherapy-induced pneumonitis (IIP) is a rare side effect but decreases patients' quality of life and often leads to permanent Immunotherapy (ICI) cessation. The diagnostic challenge is the overlapping clinical manifestations of IIP and Other types of Pneumonitis (OP), such as infectious pneumonitis. A wrong diagnosis may lead to inappropriate toxic treatment (high-dose steroids) or needless cessation of ICI. We developed a combined radiomic and clinic model to support a better differential diagnosis.