Potential of longan (Dimocarpus longan Lour.) in functional food: A review of molecular mechanism-directing health benefit properties

Longan (Dimocarpus longan Lour.) has received widespread attention worldwide as a therapeutic food with nutritional, economic, and medicinal value. Its fruit, seed, pericarp, and flower becoming dietary tools for health maintenance when it comes to targeting chronic diseases or sub-health conditions. In recent years, research focusing on longan and human health has intensified, and the high-value products of the whole fruit, including polyphenols, polysaccharides, angiotensin-I-converting enzyme (ACE)-inhibiting peptides, gamma-aminobutyric acid (GABA), and Maillard reaction products etc., may have beneficial effects on human health by preventing the onset of chronic diseases and cancer, maintaining intestinal homeostasis and skin health. Here, we review and summarize the new available evidence on the active role of phytochemicals in longan and explore the relationship between longan bioactive compounds and health benefits, with a focus on the molecular mechanisms of the health effects.