间充质干细胞
旁分泌信号
诱导多能干细胞
干细胞
再生医学
细胞生物学
商业化
化学
生物
医学
胚胎干细胞
业务
内科学
生物化学
基因
营销
受体
作者
Giuseppe Maria de Peppo
出处
期刊:Methods in molecular biology
日期:2020-01-01
卷期号:: 121-129
被引量:3
标识
DOI:10.1007/7651_2020_285
摘要
Mesenchymal stem cells (MSCs) have been used in therapies owing to their regenerative potential, paracrine regulatory effects, and immunomodulatory activity. To foster commercialization and implementation of stem cells treatments, researchers have recently derived MSCs from human induced pluripotent stem cells (iMSCs). For therapeutic applications, human iMSCs must be produced in xeno-free culture conditions and following procedures that are compatible with the principles of Good Manufacturing Practice.
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