中医药
机制(生物学)
癌症
传统医学
癌症治疗
医学
药品
药理学
生物技术
替代医学
生物
内科学
病理
认识论
哲学
作者
Zhen Jia,Xijing Zhu,Ye Zhou,Jie Wang,Mayijie Cao,C. Hu,Lingying Yu,Rui‐Hua Xu,Zhimin Chen
标识
DOI:10.1016/j.ijbiomac.2024.129423
摘要
Cancer has always been a focus of global attention, and the difficulty of treatment and poor prognosis have always plagued humanity. Conventional chemotherapeutics and treatment with synthetic disciplines will cause adverse side effects and drug resistance. Therefore, searching for a safe, valid, and clinically effective drug is necessary. At present, some natural compounds have proved to have the potential to fight cancer. Polypeptides obtained from traditional Chinese medicine are good anti-cancer ingredients. The anticancer activity has been fully demonstrated in vivo and in vitro. However, most of the functional studies on traditional Chinese medicine polypeptides are at the stage of basic experimental research, and fewer of them have been applied to clinical trials. Hence, this review mainly discusses the chemical structure, extraction, separation and purification methods, the anti-cancer mechanism, and structure–activity relationships of traditional Chinese medicine polypeptides. It provides theoretical support for strengthening the rapid separation and purification and the overall efficacy and mechanism of action, as well as the industrialization and clinical application of traditional Chinese medicine polypeptides.
科研通智能强力驱动
Strongly Powered by AbleSci AI