Characterisation of the arachidonic acid metabolising pathway in colorectal cancer

Background: Colorectal cancer is one of the most common types of cancer in the developed world. Arachidonic acid is converted by individual cytochrome P450 enzymes to epoxyeicosatrienoic acids which have been implicated in various cancer-associated biological processes. Thus, the aim of this study was to profile the expression of arachidonic acid metabolising enzymes in primary colorectal cancer and assess the association between their expression and prognosis.