Magnetic Molecularly Imprinted Polymer Preconcentration of 4-Chlorophenol with Determination by High-Performance Liquid Chromatography

A novel magnetic dummy molecularly imprinted polymer based on multiwalled carbon nanotubes was prepared with 2-amino-4-chlorophenol as the dummy template for rapid separation and enrichment of 4-chlorophenol in aqueous samples. The magnetic dummy molecularly imprinted polymer was characterized by infrared spectroscopy, transmission electron microscopy, scanning electron microscopy, and vibrating sample magnetometry. The saturation adsorption capacity of the magnetic dummy molecularly imprinted polymer toward 4-chlorophenol was up to 54.3 mg g−1 at 298 K, which is higher than for previously reported imprinted polymers. The magnetic dummy molecularly imprinted polymers were coupled with high-performance liquid chromatography to isolate and determine 4-chlorophenol in fish bile and river water with the recoveries from 95.8 to 98.9% and 96.6 to 99.1%, respectively.