Electrochemically Enabled Dehydrogenative Phosphorothiolation of 2H‐Indazoles under Electrolyte‐Free Conditions

Abstract We have developed an electrochemical method for phosphorothiolation of 2 H ‐indazoles using S ‐hydrogen phosphorothioates via cross dehydrogenative coupling reaction under metal‐free and electrolyte‐free conditions. This protocol is compatible with electron donating groups like −Me, −OMe, halogen and elctron withdrawing groups such as −COOEt, affording respective indazolyl phosphorothioates in 62%‐91% yields. Comprehensive mechanistic studies indicate that the reaction proceeds through a radical pathway. magnified image