肾
病理
CD14型
纤维化
免疫系统
医学
巨噬细胞
川地34
祖细胞
川地163
免疫学
生物
癌症研究
干细胞
内科学
细胞生物学
生物化学
体外
作者
Xiangyang Zhu,Nattawat Klomjit,Aditya S. Pawar,Amrutesh S. Puranik,Zhi-Zhang Yang,Esther Lutgens,Alfonso Eirin,Amir Lerman,Stephen C. Textor,Lilach O. Lerman
出处
期刊:American Journal of Physiology-renal Physiology
[American Physical Society]
日期:2023-11-30
卷期号:326 (2): F257-F264
被引量:2
标识
DOI:10.1152/ajprenal.00234.2023
摘要
Renal artery stenosis (RAS) is a major cause of ischemic kidney disease, which is largely mediated by inflammation. Mapping the immune cell composition in ischemic kidneys might provide useful insight into the disease pathogenesis and uncover therapeutic targets. We used mass cytometry (CyTOF) to explore the single-cell composition in a unique data set of human kidneys nephrectomized due to chronic occlusive vascular disease (RAS,
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