哮喘
单核苷酸多态性
医学
遗传关联
连锁不平衡
表达数量性状基因座
全基因组关联研究
等位基因
肿瘤科
遗传学
基因
内科学
基因型
生物
作者
Xingnan Li,Huashi Li,Stephanie A. Christenson,Mario Castro,Loren C. Denlinger,Serpil C. Erzurum,John V. Fahy,Benjamin Gaston,Elliot Israel,Nizar N. Jarjour,Bruce D. Levy,David T. Mauger,Wendy C. Moore,Joe Zein,Naftali Kaminski,Sally E. Wenzel,Prescott G. Woodruff,Eugene R. Bleecker,Deborah A. Meyers
标识
DOI：10.1080/02770903.2023.2193631
摘要
Objective Genome-wide association studies (GWASs) have identified single nucleotide polymorphisms (SNPs) in chr11p15.5 region associated with asthma and idiopathic interstitial pneumonias (IIPs). We sought to identify functional genes for asthma by combining SNPs and mRNA expression in bronchial epithelial cells (BEC) in the Severe Asthma Research Program (SARP).
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