C-reactive protein level association with future cardiovascular events assessed by different risk scores among rheumatoid arthritis patients

We appreciate the interest of Noriaki Kou and colleagues [ [1] Kou N Shimoda T Imanishi R Kanazawa H Ito H An elevated C-reactive protein level was associated with cardiovascular events among rheumatoid arthritis patients: What’s next?. Eur J Intern Med. 2022; https://doi.org/10.1016/j.ejim.2022.11.032 Abstract Full Text Full Text PDF Scopus (1) Google Scholar ] in our article [ [2] Erre G.L. Cacciapaglia F. Sakellariou G. et al. C-reactive protein and 10-year cardiovascular risk in rheumatoid arthritis. Eur J Intern Med. 2022; 104: 49-54https://doi.org/10.1016/j.ejim.2022.07.001 Abstract Full Text Full Text PDF PubMed Scopus (8) Google Scholar ], and we fully agree that beside disease activity, therapies, and systemic inflammation other non-traditional cardiovascular risk factors such as extra-articular manifestations and positivity for anti-citrullinated peptide antibodies (ACPA) and rheumatoid factor (RF) would negatively impact on the risk of future cardiovascular events in the RA population.