Synthesis of Fused Polycyclic 4‐Anilinoquinazolines and N‐Quinazoline‐Indoles via Selective C−H Bond Activation

Abstract An efficient rhodium(III)‐catalyzed site‐selective functionalization of 4‐anilinoquinazolines offers exciting possibilities for fused polycyclic 4‐anilinoquinazoline derivatives and N ‐quinazoline‐indoles by using diazo compounds as the elegant coupling partners. This one‐pot cascade approach to establish various complex 4‐anilinoquinazoline units with potential biological activities only depends on substrates and additives. magnified image