化学
特罗洛克
抗氧化剂
亚硝酸钠
神经保护
氧化应激
体内
药理学
生物化学
有机化学
抗氧化能力
医学
生物技术
生物
作者
Guangjun Yu,Yichun Shi,Shiqin Cong,Chengxun Wu,Fei Liu,Yanghui Zhang,Hongyan Liu,Xiuxiu Liu,Haixing Deng,Zhenghuai Tan,Yong Deng
标识
DOI：10.1016/j.ejmech.2023.116099
摘要
A series of butylphthalide and scutellarein hybrids 3-(alkyl/alkenyl) hydroxyphthalide derivatives were designed, synthesized and evaluated as multifunctional agents against Alzheimer's disease. In vitro bioactivity assays indicated that most of the compounds displayed excellent antioxidant activity and moderate to good inhibition activities of self-induced Aβ
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