In this paper, the distribution, removal and binding forms of heavy metals in polluted seeds of rice were studied using the methods of histochemistry and biochemistry. The results indicate that the distribution of heavy metals in rice grains was very uneven. The heavy metals in rice grains chiefly exist in association with the parts of high protein. Separation of proteins by Sephadex chromatography and subsequent analysis by atomic absorption spectroscopy revealed that Cd, Pb and As were mainly bound to protein of 54.5 and 5.50 kD molecular weights. During the rice processing, the concentrations of heavy metals in the edible rice decrease greatly, for some heavy metals in these parts of chaff, coarse rice bran and fine rice bran were removed.