Sarcopenia and associated factors in older adults with COPD: Results from the SABE-Bogota cohort study

肌萎缩 医学 慢性阻塞性肺病 腰围 人体测量学 逻辑回归 内科学 萧条(经济学) 多元分析 握力 队列 物理疗法 体质指数 宏观经济学 经济
作者
Carlos Andrés Celis Preciado,Miguel Germán Borda,Mario Pérez-Cepeda,Carlos Cano
标识
DOI:10.1183/13993003.congress-2016.oa271
摘要

Background: Sarcopenia is recognised as a clinical syndrome with multiple contributing factors. Generalised loss of muscle mass and reduced function are common in COPD but are usually studied in isolation. Aim and objective: The aim of this study is to describe the relationship between sarcopenia and COPD. Methods: We analyzed data from the SABE-Study, a cross-sectional study that included 2,000 subjects (≥60 years). COPD was determined with self report. As part of the anthropometric evaluation of the study participants, walking speed, handgrip strength, BMI and calf circumference waist were determined, measures that were used to estimate sarcopenia according de European consensus. Socio-demographic and self-report of health status were included. After bivariate models we made a multivariate regression model. Results: Of the 2000 subjects, 334 subjects had COPD (16,7%); 47% age >70 years, mean BMI 27,5, 45% with previous/actual smoking, 72% with wood smoke exposure, 28% with history of falls, 74% with depression, 22% with self perception of low nutrition. Sarcopenia was diagnosed in 105 patients (5%). In the group of COPD, sarcopenia was more frequent 11,2% vs. 6,12% (p=0,004), and patients with sarcopenia and COPD had reduced hand grip, gait speed and calf circunference (p=0,001) and worse health status compared with patients without COPD (p<0.001). In the multivariate logistic regression analysis, sarcopenia remained as an independent factor, OR of 1,81 (95%CI 1,07-3,06). Conclusions: Sarcopenia affects 11% of patients with COPD and impairs functional performance and health status. Future longitudinal studies are required to examine its impact on adverse events/survival.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
壮观采文完成签到,获得积分10
3秒前
KIORking发布了新的文献求助10
4秒前
5秒前
张建发布了新的文献求助10
6秒前
Hello应助丹丹采纳,获得10
6秒前
12秒前
KIORking完成签到,获得积分10
13秒前
13秒前
安澜完成签到,获得积分20
13秒前
dsfsd发布了新的文献求助10
14秒前
14秒前
16秒前
16秒前
张涛发布了新的文献求助10
17秒前
酷波er应助Lee采纳,获得10
19秒前
呆瓜完成签到,获得积分10
21秒前
22秒前
小马的可爱老婆2完成签到,获得积分10
22秒前
授业解惑的哑铃完成签到,获得积分10
23秒前
ni完成签到,获得积分10
23秒前
木木完成签到,获得积分10
25秒前
25秒前
25秒前
25秒前
26秒前
凌辰完成签到,获得积分10
27秒前
28秒前
木木发布了新的文献求助10
29秒前
DH完成签到 ,获得积分10
29秒前
青山完成签到,获得积分10
30秒前
正直凌文发布了新的文献求助10
30秒前
量子星尘发布了新的文献求助10
30秒前
王星星发布了新的文献求助10
30秒前
Lee发布了新的文献求助10
32秒前
共享精神应助123采纳,获得10
32秒前
Heisenberg完成签到,获得积分10
32秒前
静夜澜迷失完成签到 ,获得积分10
32秒前
风平浪静发布了新的文献求助10
33秒前
酷酷的采珊完成签到,获得积分10
34秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3988975
求助须知:如何正确求助?哪些是违规求助? 3531316
关于积分的说明 11253424
捐赠科研通 3269917
什么是DOI,文献DOI怎么找? 1804830
邀请新用户注册赠送积分活动 882063
科研通“疑难数据库(出版商)”最低求助积分说明 809068