| 标题 |
 Bifunctional Electrospun Nanocomposite Dressing: Integrating Antibacterial Efficacy and Controllable Antioxidant Properties for Expedited Wound Healing 双功能电纺纳米复合敷料：整合抗菌功效和可控抗氧化性能加速伤口愈合
相关领域
材料科学
双功能
伤口愈合
纳米复合材料
伤口敷料
氧化铈
铈
抗菌活性
纳米技术
复合材料
氧化物
有机化学
医学
冶金
化学
细菌
外科
催化作用
生物
遗传学
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| 网址 | |
| DOI | |
| 其它 | Current wound dressings are insufficient in simultaneously addressing bacterial infections and oxidative stress, which severely affects wound healing outcomes. To solve this problem, we introduced poly(ionic liquid) (PIL) with strong antibacterial properties and cerium oxide nanoparticles (CeO2NPs) with excellent antioxidant capabilities into polyacrylonitrile (PAN) nanofiber membranes to prepare a novel composite dressing. The PIL-CeO2NPs-PAN nanofiber membrane provides sustained antibacterial activity through stably embedded PIL, while the uniformly distributed CeO2NPs achieve controlled release, avoiding safety issues caused by the rapid release of active substances. In vitro and in vivo experiments demonstrated that the membrane exhibits outstanding biocompatibility, significant antibacterial effects (inhibition rates of 88.3% against Escherichia coli and 93.2% against Staphylococcus aureus), and excellent antiox |
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